Volume 12, Number 3, March 2006

Identifying and Quantifying Genotypes in Polyclonal Infections due to Single Species

James M. Colborn,* Ousmane A. Koita,† Ousmane Cissé,† Mamadou W. Bagayoko,† Edward J. Guthrie,‡ and Donald J. Krogstad*
*Tulane University Health Sciences Center, New Orleans, Louisiana, USA; †University of Bamako, Bamako, Mali; and ‡Agilent Technologies, Wilmington, Delaware, USA

Figure 2. Copy numbers for genotypes of the K1 allotype in 10 field samples. Distribution of K1 genotypes within the 8 patients whose samples yielded amplicons with K1-specific primers (Table 4 ). These results indicate that most infected persons had >2 allotypes. In addition, persons with K1 allotype parasites had a high degree of genotypic complexity, that is, capillary electrophoresis showed up to 4 distinct K1 genotypes in the blood of individual patients at the same time.

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This page last reviewed February 14, 2006

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention