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Volume 10, Number 10, October 2004

Dihydropteroate Synthase Gene Mutations in Pneumocystis and Sulfa Resistance

Laurence Huang,* Kristina Crothers,* Chiara Atzori,† Thomas Benfield,‡ Robert Miller,§ Meja Rabodonirina,¶ and Jannik Helweg-Larsen#
*University of California San Francisco, San Francisco, California, USA; †Luigi Sacco Hospital, Milan, Italy; ‡HS Rigshospitalet, Copenhagen, Denmark; §University College London, London, United Kingdom; ¶Hôspital de la Croiz-Rousse, Lyon, France; and #Hvidovre University Hospital, Copenhagen, Denmark

 
 
Figure.
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Figure. Inhibition of folate synthesis by sulfonamides and trimethoprim. PABA, paraaminobenzoic acid; DHPS, dihydropteroate synthase; DHFR, dihydrofolate reductase.

 

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This page last reviewed August 31, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
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