Understanding the Excess of Bladder Cancers in Northern New England
New Hampshire State Cancer Registry
A partnership between the National Cancer Institute, Dartmouth Medical School, and the Maine, New Hampshire, and Vermont state cancer registries performed a case control study examining bladder cancer risk in relation to smoking practices. The study was based on interview data from a large, population-based case-control study conducted in Maine, New Hampshire, and Vermont from 2001 to 2004. To examine changes in smoking-induced bladder cancer risk over time, researchers compared odds ratios from New Hampshire residents in this study with those from two case-control studies conducted in New Hampshire in 1994–1998 and in 1998–2001.
Bladder cancer risk associated with smoking appears to have increased for New Hampshire residents since the mid-1990s. The study also showed that smoking fewer cigarettes over a long time appears more harmful than smoking more cigarettes over a shorter time. Publication of these data contributes to our knowledge of smoking in bladder cancer etiology and public health prevention efforts.
Baris D, Karagas MR, Verrill C, Johnson A, Andrew AS, Marsit CJ, Schwenn M, Colt JS, Cherala S, Samanic C, Waddell R, Cantor KP, Schned A, Rothman N, Lubin J, Fraumeni JF Jr, Hoover RN, Kelsey KT, Silverman DT. A case-control study of smoking and bladder cancer risk: emergent patterns over time. Journal of the National Cancer Institute 2009;101(22):1553–1561.