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2003 Assisted Reproductive Technology (ART) Report: Section 2—ART Cycles Using Fresh, Nondonor Eggs or Embryos


Explanation of Figures, Section 2: ART Cycles Using Fresh, Nondonor Eggs or Embryos

This page contains figures 25–35 of Section 2C 
Click on titles or images to go back to Section 2C


What are the success rates for couples with male factor infertility when ICSI is used?

Figure 25

Figure 25 text below

Figure 25 is a bar graph representing percentage of live births per retrieval for ART cycles using fresh nondonor eggs or embryos among couples diagnosed with male factor infertility who used IVF with ICSI (intracytoplasmic sperm injection) in comparison to IVF without ICSI, by woman’s age, 2003. Note: Cycles using donor sperm and cycles using GIFT or ZIFT are excluded. The comparison group of IVF without ICSI includes couples with all diagnoses except male factor infertility.

  • Age <35, IVF without ICSI 42.6%, IVF with ICSI 41.8%
  • Age 35–37, IVF without ICSI 35.9%, IVF with ICSI 35.0%
  • Age 38–40, IVF without ICSI 26.2%, IVF with ICSI 24.1%
  • Age 41–42, IVF without ICSI 16.1%, IVF with ICSI 13.5%
  • Age >42, IVF without ICSI 6.0%, IVF with ICSI 4.2%
     

What are the success rates for couples without a diagnosis of male factor infertility when ICSI is used?

Figure 26

Figure 26 text below

Figure 26 is a bar graph representing the percentage of live births per retrieval for ART cycles using fresh nondonor eggs or embryos among couples not diagnosed with male factor infertility, by use of ICSI (intracytoplasmic sperm injection) and woman’s age, 2003. Note: Cycles using GIFT and ZIFT are excluded.

  • Age <35, IVF without ICSI 42.6%, IVF with ICSI 37.8%
  • Age 35–37, IVF without ICSI 35.9%, IVF with ICSI 32.2%
  • Age 38–40, IVF without ICSI 26.2%, IVF with ICSI 21.8%
  • Age 41–42, IVF without ICSI 16.1%, IVF with ICSI 11.0%
  • Age >42, IVF without ICSI 6.0%, IVF with ICSI 4.2%
     

How many embryos are transferred in an ART procedure?

Figure 27

Figure 27 text below

Figure 27 is a pie chart representing the number of embryos transferred during ART cycles using fresh nondonor eggs or embryos, 2003.

  • One, 7.5%
  • Two, 36.2%
  • Three, 32.7%
  • Four, 15.6%
  • Five, 5.1%
  • Six, 1.9%
  • Seven or more, 0.9%
     

In general, is an ART cycle more likely to be successful if more embryos are transferred?

Figure 28

Figure 28 text below

Figure 28 is a bar graph representing the percentage of live births per transfer and the percentages of multiple-infant births for ART cycles using fresh nondonor eggs or embryos, by number of embryos transferred, 2003. Note: In rare cases a single embryo may divide and thus produce twins. For this reason a small percentage of twins resulted from a single embryo transfer and a small percentage of triplets resulted when two embryos were transferred.

  • 1 Embryo transferred, Live births per transfer 13.2%. Of these live births, 97.7% were singletons and 2.3% were twins.
  • 2 Embryos transferred, Live births per transfer 40.2%. Of these live births, 67.1% were singletons, 32.0% were twins and 0.9% were triplets or more.
  • 3 Embryos transferred, Live births per transfer 36.9%. Of these live births, 62.9% were singletons, 32.0% were twins and 5.2% were triplets or more.
  • 4 Embryos transferred, Live births per transfer 32.0%. Of these live births, 62.9% were singletons, 32.2% were twins and 4.9% were triplets or more.
  • 5 or more Embryos transferred, Live births per transfer 26.6%. Of these live births, 66.0% were singletons, 29.5% were twins and 4.5% were triplets or more.

     

Are live birth rates affected by the number of embryos transferred for women who have more embryos available than they choose to transfer?

Figure 29

Figure 29 text below

Figure 29 is a bar graph representing live births per transfer and percentages of multiple-infant births for ART cycles in women who were younger than 35; used fresh nondonor eggs or embryos, and set aside extra embryos for future use, by number of embryos transferred, 2003. Note: In rare cases, a single embryo may divide and thus produce twins. For this reason, a small percentage of twins resulted from a single embryo transfer and a small percentage of triplets resulted when two embryos were transferred.

  • 1 Embryo transferred, Live births per transfer 39.5%. Of these live births, 99.0% were singletons, 1.0% were twins.
  • 2 Embryos transferred, Live births per transfer 53.3%. Of these live births, 60.5% were singletons, 38.6% were twins and 0.9% were triplets or more.
  • 3 Embryos transferred, Live births per transfer 49.2%. Of these live births, 53.9% were singletons, 37.8% were twins and 8.3% were triplets or more.
  • 4 Embryos Transferred, Live births per transfer 45.9%. Of these live births, 43.5% were singletons, 46.7% were twins and 9.9% were triplets or more.
  • 5 or more Embryos transferred, Live births per transfer 48.2%. Of these live births, 48.2% were singletons, 41.7% were twins and 10.2% were triplets or more.
     

How long after egg retrieval does embryo transfer occur?

Figure 30

Figure 30 text below

Figure 30 is a pie chart representing the day of embryo transfer among ART cycles using fresh nondonor eggs or embryos, 2003. Note: Day of embryo transfer is defined as the number of days following egg retrieval. Cycles using GIFT and ZIFT are excluded. Missing or implausible values for day of embryo transfer (i.e., 0 or >6) are not included in these statistics.

  • Day 1, 0.1%
  • Day 2, 4.1%
  • Day 3, 72.7%
  • Day 4, 3.8%
  • Day 5, 17.6%
  • Day 6, 1.7%
     

In general, is an ART cycle more likely to be successful if embryos are transferred on day 5?

Figure 31

Figure 31 text below

Figure 31 is a bar graph representing live births per transfer for ART cycles using fresh nondonor eggs or embryos, for day 3 and day 5 embryo transfers, 2003. Note: Cycles using GIFT and ZIFT are excluded. This comparison is limited to transfers on day 3 and day 5. Embryo transfers performed on days 1, 2, 4, and 6 are not included because each of these accounted for a small proportion of procedures.

  • Age <35, day 3 42.1%, day 5 49.6%
  • Age 35–37, day 3 35.4%, day 5 44.9%
  • Age 38–40, day 3 25.5%, day 5 32.2%
  • Age 41–42, day 3 14.7%, day 5 20.5%
  • Age >42, day 3 6.0%, day 5 6.7%
     

Does the number of embryos transferred differ for day 3 and day 5 embryo transfers?

Figure 32

Figure 32: text below

Figure 32 consists of two pie charts representing the number of embryos transferred during ART cycles using fresh nondonor eggs or embryos for day 3 and day 5 embryo transfers, 2003. Note: Cycles using GIFT and ZIFT are excluded. This comparison is limited to transfers on day 3 and day 5. Embryo transfers performed on days 1, 2, 4, and 6 are not included because each of these accounted for a small proportion of procedures.

  • Day 3:
    • 1 Embryo transferred, 6.9%
    • 2 Embryos transferred, 29.2%
    • 3 Embryos transferred, 35.9%
    • 4 or more Embryos transferred, 27.9%
  • Day 5:
    • 1 Embryo transferred, 7.0%
    • 2 Embryos transferred, 66.0%
    • 3 Embryos transferred, 21.2%
    • 4 or more Embryos transferred, 5.9%

In general, how does the multiple-birth risk vary by the day of embryo transfer?

Figure 33

Figure 33: text below

Figure 33 depicts two pie charts, A and B, representing the risk of having multiple-infant live birth for ART cycles using fresh nondonor eggs or embryos for day 3 and day 5 embryo transfers, 2003. Note: Cycles using GIFT and ZIFT are excluded. This comparison is limited to transfers on day 3 and day 5. Embryo transfers performed on days 1, 2, 4, and 6 are not included because each of these accounted for a small proportion of procedures.

  • Pie chart A represents 17,681 live births
    • Singletons: 66.6%
    • Total multiple-infant live births 33.3%, which are further subdivided as follows:
      • Twins: 29.9%
      • Triplets or more: 3.4%
  • Pie chart B represents 5,705 live births
    • Singletons: 61.9%
    • Total multiple-infant live births 38.2%, which are further subdivided as follows:
      • Twins: 36.0%
      • Triplets or more: 2.2%

What are the success rates for women who use gestational carriers?

Figure 34

Figure 34: text below

 

Figure 34 is a bar graph representing a comparison of live births per transfer between cycles that used gestational carriers and those that did not (both using fresh nondonor embryos), by ART patient’s age, 2003.
Note: Age categories reflect the age of the ART patient, not the age of the gestational carrier.

  • Age <35, did not use gestational carrier, 43.1%
  • Age <35, used gestational carrier, 50.6%
  • Age 35–37, did not use gestational carrier, 36.5%
  • Age 35–37, used gestational carrier, 44.5%
  • Age 38–40, did not use gestational carrier, 26.1%
  • Age 38–40, used gestational carrier, 21.9%
  • Age >40, did not use gestational carrier, 12.1%
  • Age >40, used gestational carrier, 18.5%
Note: We were unable to further subdivide age >40 because the number of such cycles is very small.
 


How is clinic size related to success rates?

Figure 35

Figure 35: text below

 

 

 

 

 

 

 

 

 

Figure 35 is a bar graph representing live birth rates for ART cycles using fresh nondonor eggs or embryos, by clinic size, 2003. Note: clinic size is determined by number of cycles performed in 2003.

  • Clinic size <61, 25.8%
  • Clinic size 61–131, 29.2%
  • Clinic size 132–258, 29.1%
  • Clinic size >258, 28.1%

Section 1 | Section 2 | Section 3 | Section 4 | Section 5

 
Selected Resources

Previous ART Reports

Implementation of the Fertility Clinic Success Rate and Certification Act of 1992

Assisted Reproductive Technology: Embryo Laboratory

Date last reviewed: 03/27/2006
Content source: Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion

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